Lapho sihlangana nemishini yezokwelapha, izitho zokwenziwa noma izinto zokuhlinza, sivame ukuqaphela ukuthi yiziphi izinto ezenziwe ngazo. Phela, izinto esizikhethayo zibalulekile. Irabha ye-Silicone iyinto esetshenziswa kabanzi emkhakheni wezokwelapha, futhi izici zayo ezinhle kakhulu ze-biocompatibility kufanele zihlolwe ngokujulile. Lesi sihloko sizohlola ngokujulile i-biocompatibility yerabha ye-silicone kanye nokusetshenziswa kwayo emkhakheni wezokwelapha.
Irabha ye-Silicone iyi-high-molecular organic material equkethe amabhondi e-silicon namabhondi ekhabhoni esakhiweni sayo samakhemikhali, ngakho-ke ithathwa njengezinto ezingaphili. Emkhakheni wezokwelapha, irabha ye-silicone isetshenziswa kabanzi ukwenza izinsiza zezokwelapha ezahlukahlukene kanye nezinto zokwelapha, njengamalunga okwenziwa, ama-pacemaker, amabele okufakelwa, ama-catheter kanye nama-ventilators. Esinye sezizathu eziyinhloko zokuthi kungani irabha ye-silicone isetshenziswa kabanzi yi-biocompatibility yayo enhle kakhulu.
I-biocompatibility yerabha ye-silicone ngokuvamile ibhekisela esimweni sokusebenzelana phakathi kwezinto ezibonakalayo nezicubu zomuntu, igazi nolunye uketshezi lwebhayoloji. Phakathi kwazo, izinkomba ezivame kakhulu zihlanganisa i-cytotoxicity, impendulo yokuvuvukala, impendulo yokuzivikela komzimba kanye ne-thrombosis.
Okokuqala, i-cytotoxicity yerabha ye-silicone iphansi kakhulu. Lokhu kusho ukuthi uma irabha ye-silicone ihlangana namaseli omuntu, ngeke ibangele imiphumela emibi kuwo. Esikhundleni salokho, iyakwazi ukusebenzisana namaprotheni e-cell surface futhi ikhuthaze ukuvuselelwa kwezicubu nokulungisa ngokuzibophezela kubo. Lo mphumela wenza irabha ye-silicone ibe yinto ebalulekile emikhakheni eminingi ye-biomedical.
Okwesibili, irabha ye-silicone nayo ayibangeli impendulo ebalulekile yokuvuvukala. Emzimbeni womuntu, impendulo yokuvuvukala iyindlela yokuzivikela eqalwa lapho umzimba ulimala noma utheleleke ukuvikela umzimba ekulimaleni okuqhubekayo. Kodwa-ke, uma impahla ngokwayo ibangela impendulo yokuvuvukala, ayifanele ukusetshenziswa emkhakheni wezokwelapha. Ngenhlanhla, irabha ye-silicone ine-reactivity ephansi kakhulu yokuvuvukala futhi ngenxa yalokho ayibangeli umonakalo omkhulu emzimbeni womuntu.
Ngaphezu kwe-cytotoxicity kanye nokuphendula kokuvuvukala, irabha ye-silicone iyakwazi nokunciphisa ukuphendula komzimba. Emzimbeni womuntu, amasosha omzimba ayindlela evikela umzimba kuma-pathogens angaphandle nezinye izinto eziyingozi. Kodwa-ke, lapho izinto zokwenziwa zingena emzimbeni, amasosha omzimba angase azibone njengezinto zangaphandle futhi aqalise ukusabela komzimba. Lokhu kusabela komzimba kungase kubangele ukuvuvukala okungadingekile kanye neminye imiphumela emibi. Ngokuphambene nalokho, impendulo yokuzivikela komzimba yerabha ye-silicone iphansi kakhulu, okusho ukuthi ingaba khona emzimbeni womuntu isikhathi eside ngaphandle kokubangela noma yikuphi ukusabela komzimba.
Ekugcineni, irabha ye-silicone nayo inezindawo zokulwa ne-thrombotic. I-Thrombosis yisifo esenza igazi lijiye futhi lenze amahlule. Uma ihlule legazi liphuka futhi lithuthelwa kwezinye izingxenye, lingabangela isifo senhliziyo, unhlangothi, nezinye izinkinga zempilo ezimbi kakhulu. Irabha ye-Silicone ingavimbela i-thrombosis futhi ingasetshenziswa kumadivayisi afana nama-valve enhliziyo yokwenziwa, ukuvimbela ngokuphumelelayo izinkinga zempilo ezifana nesifo senhliziyo nesifo sohlangothi.
Ngamafuphi, i-biocompatibility yerabha ye-silicone ihle kakhulu, okwenza kube yinto ebalulekile emkhakheni wezokwelapha. Ngenxa ye-cytotoxicity ephansi, i-reactivity ephansi yokuvuvukala, i-immunoreactivity ephansi kanye nezici ze-anti-thrombotic, irabha ye-silicone ingasetshenziswa kabanzi ekukhiqizeni izitho zokwenziwa, amadivaysi ezokwelapha kanye nezinto zokuhlinza, njll., ukusiza iziguli zithole imiphumela engcono yokwelashwa kanye nekhwalithi yokwelashwa. ukuphila.
Isikhathi sokuthumela: Jul-15-2024